If you want high-tier loot with multiple greater affixes, farming Belial is the most efficient option.
For Mythic farming, focus on multiple hideout bosses rather than relying solely on Belial.
Collect Spectral Ash to progress your crafting potential, since it leads to better rewards for Mythic crafting.
Consider avoiding Great Hideout bosses if you want a smoother farming experience, especially if playing solo.
Keep in mind that boss runs on torment 4 solo are viable and yield significant loot, but Diablo 4 Items expect RNG variance.
If you want, I can create a simple farming route and priority list based on this, and also suggest the best use of your Diablo 4 gold and Diablo 4 items to push faster farming runs or crafting efficiency.
Player’s Conclusions
Belial is the best boss to farm for high-quality loot, especially for 2-3 Greater Affix (GA) Uniques.
In 250 runs against Belial, the player obtained over 600 GA-Uniques and 4 Mythics, showing a strong drop rate for valuable gear.
Aspirant Hideout Bosses also offer decent Mythic drop chances, but the overall loot quantity and quality are lower than Belial’s.
After nearly 300 runs on the aspirant bosses, the player got fewer GA-Uniques and Mythics, but still useful drops.
Great Hideout Bosses (Duriel, Andariel, Herald of Hatred) are less appealing for farming due to frustrating mechanics and lower loot efficiency.
The player specifically mentioned avoiding Andariel because of Diablo 4 Items for sale its multiple immunity phases that slow down fights significantly.